Oregon State University – LUIZ E. BERMUDEZ, MD
The Oregon State University mycobacterial research program investigates the pathogenesis, host–pathogen interactions, and treatment strategies of nontuberculous mycobacterial (NTM) infections to advance scientific understanding and support development of novel therapies.
Luiz E. Bermudez, MD
Primary Investigator
Oregon State University
Institution
Mycobacterial Research Laboratory
Research Center Type
Project Overview
The Oregon State University laboratory focuses on understanding the mechanisms of mycobacterial infection and persistence, particularly in nontuberculous mycobacterial disease. Through experimental and translational approaches, the lab investigates bacterial survival strategies, host immune interactions, and therapeutic responses to support development of improved treatment strategies.
Project Summary
The research program studies Mycobacterium avium, Mycobacterium abscessus, and Mycobacterium tuberculosis, with emphasis on biofilm formation, intracellular survival, and host environmental interactions. Using cellular, animal, and molecular models, the lab explores disease mechanisms and evaluates potential therapeutic compounds to address antibiotic resistance and persistent infection.
Project Goals
- Understand mechanisms of mycobacterial pathogenesis and persistence
- Investigate biofilm formation and bacterial survival strategies
- Study host–pathogen and co-infection interactions
Impact
This research advances fundamental understanding of nontuberculous mycobacterial disease and supports the development of new therapeutic strategies by identifying key mechanisms of infection, persistence, and drug resistance.
Advancing Research. Improving Lives.
Advancing scientific discovery in mycobacterial pathogenesis and nontuberculous mycobacterial (NTM) disease through translational research focused on infection biology, biofilm formation, and host–pathogen interactions.
Project Overview
The Oregon State University laboratory focuses on understanding the mechanisms of mycobacterial infection and persistence, particularly in nontuberculous mycobacterial disease. Through experimental and translational approaches, the lab investigates bacterial survival strategies, host immune interactions, and therapeutic responses to support development of improved treatment strategies.