1: Moreira-Sousa D, Martins B, Aguiar A, Pinheiro M, Akkerman O, Aksamit TR,
Aliberti S, Andrejak C, Daley CL, van Ingen J, Lange C, Lipman M, Loebinger MR,
Jankovic Makek M, Morimoto K, Thomson RM, Wagner D, Winthrop KL, Yim JJ, Duarte
R. Consensus on Management of Refractory Nontuberculous Mycobacterial Pulmonary
Disease. Eur Respir J. 2025 Nov 6:2500400. doi: 10.1183/13993003.00400-2025.
Epub ahead of print. PMID: 41198394.
2: Daley CL, Flume PA, van Ingen J, Khare R, Mingora CM, Nguyen MH, Winthrop KL,
Zha BS. A systematic review of tetracyclines for nontuberculous mycobacteria:
focus on rapidly growing mycobacteria. Eur Respir Rev. 2025 Nov
5;34(178):250038. doi: 10.1183/16000617.0038-2025. PMID: 41193247; PMCID:
PMC12588081.
3: Napier EG, Doratt BM, Cinco IR, Stuart EV, Geron RD, Davies MH, Malherbe DC,
Kohama SG, Bermudez L, Winthrop KL, Fuss C, Spindel ER, Messaoudi I. Age-related
severity of nontuberculous mycobacterial lung disease is mediated by aberrant
macrophage responses and lung microbial dysbiosis. J Infect. 2025
Nov;91(5):106626. doi: 10.1016/j.jinf.2025.106626. Epub 2025 Oct 10. PMID:
41077197.
4: Marmor M, Brunton AE, Fraulino D, Ruoss SJ, Henkle E, Zha BS, Metersky M,
Winthrop K; Bronchiectasis and NTM Research Registry Investigators. The
Association Between Incident Nontuberculous Mycobacteria Isolation and
Antibiotic Exposure in Patients with Bronchiectasis. Chest. 2025 Oct
30:S0012-3692(25)05493-5. doi: 10.1016/j.chest.2025.09.122. Epub ahead of print.
PMID: 41076063.
5: Winthrop KL, Waweru C, Welch E, Wang P, Markson LE. Persistent use of
amikacin liposome inhalation suspension associated with lower risk of
hospitalizations and emergency room visits in refractory Mycobacterium avium
complex lung disease. Respir Med. 2025 Nov-Dec;249:108406. doi:
10.1016/j.rmed.2025.108406. Epub 2025 Oct 9. PMID: 41067294.
6: Chalmers JD, Haworth CS, Flume P, Long MB, Burgel PR, Dimakou K, Blasi F,
Herrero-Cortina B, Dhar R, Chotirmall SH, Ringshausen FC, Altenburg J, Morgan L,
Nigro M, Crichton ML, Van Meel C, Sibila O, Timothy A, Kompatsiari E, Hedberg T,
Vandendriessche T, McShane PJ, Tonia T, Winthrop K, Loebinger MR, Lorent N,
Goeminne P, Shteinberg M, Polverino E, Aliberti S. European Respiratory Society
Clinical Practice Guideline for the Management of Adult Bronchiectasis. Eur
Respir J. 2025 Sep 28:2501126. doi: 10.1183/13993003.01126-2025. Epub ahead of
print. PMID: 41016738.
7: Chalmers JD, Burgel PR, Daley CL, De Soyza A, Haworth CS, Mauger D, Loebinger
MR, McShane PJ, Ringshausen FC, Blasi F, Shteinberg M, Mange K, Teper A,
Fernandez C, Zambrano M, Fan C, Zhang X, Metersky ML; ASPEN Investigators. Phase
3 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis. N Engl J Med. 2025
Apr 24;392(16):1569-1581. doi: 10.1056/NEJMoa2411664. PMID: 40267423.
8: Daley CL, Chalmers JD, Flume PA, Griffith DE, Hasegawa N, Morimoto K,
Winthrop KL, Sheu CC, Avsar K, Andrisani D, Codecasa LR, Yuen DW, Hassan M,
Nevoret ML, Mange K. Trial Conduct, Baseline Characteristics, and Symptom Burden
of Patients in the ARISE Study. Pulm Ther. 2025 Jun;11(2):269-283. doi:
10.1007/s41030-025-00293-3. Epub 2025 Apr 8. PMID: 40198465; PMCID: PMC12102049.
9: Winthrop KL, Mingora CM, Varley CD, Dorman SE, Flume PA. Relationship between
culture conversion and clinical outcomes in nontuberculous mycobacterial
pulmonary disease: Narrative review. Respir Med. 2025 May;241:108052. doi:
10.1016/j.rmed.2025.108052. Epub 2025 Mar 23. PMID: 40132751.
10: Metersky ML, Losier AJ, Fraulino DA, Warnock TA, Varley CD, Le AM, Winthrop
KL, McArdle JR, Shakir SM, Khare R. Mycobacterium nebraskense Isolated from
Patients in Connecticut and Oregon, USA. Emerg Infect Dis. 2025
Mar;31(3):507-515. doi: 10.3201/eid3103.240608. PMID: 40023800; PMCID:
PMC11878316.
11: Chaccour C, Sánchez-Olivieri I, Siegel S, Megson G, Winthrop KL, Botella JB,
de-Torres JP, Jover L, Brew J, Kafentzis G, Galvosas M, Rudd M, Small P.
Validation and accuracy of the Hyfe cough monitoring system: a multicenter
clinical study. Sci Rep. 2025 Jan 6;15(1):880. doi: 10.1038/s41598-025-85341-3.
PMID: 39762316; PMCID: PMC11704278.
12: Varley CD, Ku JH, Henkle E, Strnad L, Winthrop KL. <i>The Long and Winding
Road</i>: Three-year Mortality Following Prescription of Multidrug Antibiotic
Treatment for <i>Mycobacterium avium complex</i> Pulmonary Disease in United
States Medicare Beneficiaries With Bronchiectasis. Open Forum Infect Dis. 2024
Nov 6;11(11):ofae639. doi: 10.1093/ofid/ofae639. PMID: 39582505; PMCID:
PMC11584409.
13: Lapinel NC, Choate R, Aksamit TR, Feliciano J, Winthrop KL, Schmid A, Fucile
S, Metersky ML. Characteristics of exacerbators in the US Bronchiectasis and NTM
Research Registry: a cross-sectional study. ERJ Open Res. 2024 Nov
11;10(6):00185-2024. doi: 10.1183/23120541.00185-2024. PMID: 39534769; PMCID:
PMC11551853.
14: Bents SJ, Mercaldo RA, Powell C, Henkle E, Marras TK, Prevots DR.
Nontuberculous mycobacterial pulmonary disease (NTM PD) incidence trends in the
United States, 2010-2019. BMC Infect Dis. 2024 Oct 2;24(1):1094. doi:
10.1186/s12879-024-09965-y. PMID: 39358723; PMCID: PMC11445848.
15: Haworth CS, Shteinberg M, Winthrop K, Barker A, Blasi F, Dimakou K, Morgan
LC, O’Donnell AE, Ringshausen FC, Sibila O, Thomson RM, Carroll KJ, Pontenani F,
Castellani P, Chalmers JD; PROMIS trial investigators. Inhaled colistimethate
sodium in patients with bronchiectasis and Pseudomonas aeruginosa infection:
results of PROMIS-I and PROMIS-II, two randomised, double-blind, placebo-
controlled phase 3 trials assessing safety and efficacy over 12 months. Lancet
Respir Med. 2024 Oct;12(10):787-798. doi: 10.1016/S2213-2600(24)00225-X. Epub
2024 Sep 10. PMID: 39270696.
16: Li L, Henkle E, Youngquist BM, Seo S, Hamed K, Melnick D, Lyon CJ, Jiang L,
Zelazny AM, Hu TY, Winthrop KL, Ning B. Serum Cell-Free DNA-based Detection of
<i>Mycobacterium avium</i> Complex Infection. Am J Respir Crit Care Med. 2024
May 15;209(10):1246-1254. doi: 10.1164/rccm.202303-0401OC. Erratum in: Am J
Respir Crit Care Med. 2024 Sep 1;210(5):697. doi: 10.1164/rccm.v210erratum2.
PMID: 38190702; PMCID: PMC11146540.
17: Cristancho-Rojas C, Varley CD, Lara SC, Kherabi Y, Henkle E, Winthrop KL.
Epidemiology of Mycobacterium abscessus. Clin Microbiol Infect. 2024
Jun;30(6):712-717. doi: 10.1016/j.cmi.2023.08.035. Epub 2023 Sep 30. PMID:
37778416.
18: Kwak N, Henkle E, Hwang H, Jeon D, Jhun BW, Jo KW, Kang YA, Kim HJ, Kim JY,
Kim YR, Kwon YS, Lee JH, Mok J, Park Y, Shim TS, Sohn H, Whang J, Yim JJ.
Improvement in Health-Related Quality of Life Following Antibiotic Treatment in
Nontuberculous Mycobacterial Pulmonary Disease: Initial Analysis of the NTM-
KOREA Cohort. Clin Infect Dis. 2024 Jun 14;78(6):1690-1697. doi:
10.1093/cid/ciae131. PMID: 38563246.
19: Ku JH, Henkle E, Carlson KF, Marino M, Brode SK, Marras TK, Winthrop KL.
Tolerability Outcomes of American Thoracic Society/Infectious Diseases Society
of America Guideline-Recommended Multidrug Antibiotic Treatment for
Mycobacterium avium Complex Pulmonary Disease in US Medicare Beneficiaries With
Bronchiectasis. Chest. 2024 May;165(5):1058-1069. doi:
10.1016/j.chest.2023.12.006. Epub 2023 Dec 10. PMID: 38086472; PMCID:
PMC11214905.
20: Grigg C, Jackson KA, Barter D, Czaja CA, Johnston H, Lynfield R, Vagnone PS,
Tourdot L, Spina N, Dumyati G, Cassidy PM, Pierce R, Henkle E, Prevots DR,
Salfinger M, Winthrop KL, Toney NC, Magill SS. Epidemiology of Pulmonary and
Extrapulmonary Nontuberculous Mycobacteria Infections at 4 US Emerging
Infections Program Sites: A 6-Month Pilot. Clin Infect Dis. 2023 Aug
22;77(4):629-637. doi: 10.1093/cid/ciad214. PMID: 37083882; PMCID: PMC10444004.
21: Henkle E, Quittner AL, Dieckmann NF, Franklin H, Brunton AE, Daley CL,
Winthrop KL; MAC2v3 Investigators. Patient-Reported Symptom and Health-Related
Quality-of-Life Validation and Responsiveness During the First 6 Months of
Treatment for Mycobacterium avium Complex Pulmonary Disease. Chest. 2023
Jul;164(1):53-64. doi: 10.1016/j.chest.2023.02.015. Epub 2023 Feb 17. PMID:
36803647; PMCID: PMC10329268.
22: Flume PA, Basavaraj A, Garcia B, Winthrop K, Di Mango E, Daley CL, Philley
JV, Henkle E, O’Donnell AE, Metersky M. Towards development of evidence to
inform recommendations for the evaluation and management of bronchiectasis.
Respir Med. 2023 May;211:107217. doi: 10.1016/j.rmed.2023.107217. Epub 2023 Mar
16. PMID: 36931575.
23: Ku JH, Henkle E, Carlson KF, Marino M, Brode SK, Marras TK, Winthrop KL.
Evaluation of Mycobacterium Avium Complex Pulmonary Disease Treatment Completion
and Adherence to ATS/IDSA Guidelines. Clin Infect Dis. 2023 Feb
8;76(3):e1408-e1415. doi: 10.1093/cid/ciac394. PMID: 35607719.
24: Ku JH, Henkle E, Aksamit TR, Barker A, Brunton AE, Winthrop KL;
Bronchiectasis and NTM Research Registry investigators. Treatment of
Nontuberculous Mycobacterial (NTM) Pulmonary Infection in the US Bronchiectasis
and NTM Registry: Treatment Patterns, Adverse Events, and Adherence to American
Thoracic Society/Infectious Disease Society of America Treatment Guidelines.
Clin Infect Dis. 2023 Jan 13;76(2):338-341. doi: 10.1093/cid/ciac788. PMID:
36134755.
25: Hernandez AG, Brunton AE, Ato M, Morimoto K, Machida S, Henkle E, Winthrop
KL. Use of Anti-Glycopeptidolipid-Core Antibodies Serology for Diagnosis and
Monitoring of <i>Mycobacterium avium</i> Complex Pulmonary Disease in the United
States. Open Forum Infect Dis. 2022 Oct 22;9(11):ofac528. doi:
10.1093/ofid/ofac528. PMID: 36349274; PMCID: PMC9636853.