UNIVERSITY OF CALIFORNIA, SAN FRANCISCO – SHOSHANA ZHA, MD
This research program advances multidisciplinary care and translational research for bronchiectasis and pulmonary nontuberculous mycobacterial (NTM) disease, with a focus on host susceptibility, macrophage responses, and innovative therapeutic strategies.
B. SHOSHANA ZHA, MD
Primary Investigator
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (UCSF)
Institution
INTEGRATE BRONCHIECTASIS & PULMONARY NTM PROGRAM
Research Center Type
Project Overview
INTEGRATE is a multidisciplinary clinical and research program focused on improving the understanding, diagnosis, and treatment of bronchiectasis and pulmonary NTM disease. The center combines expertise in pulmonary medicine, infectious diseases, microbiology, immunology, and translational science to provide integrated patient-centered care and innovative research initiatives.
Project Summary
The UCSF research team conducts translational, mechanistic, and clinical studies focused on host susceptibility to NTM infection, macrophage immune responses, healthcare disparities, and treatment outcomes. Research includes prospective registries, biorepositories, NIH-supported investigations, and industry-sponsored clinical trials designed to improve therapies and long-term patient care.
Project Goals
- To improve understanding of susceptibility to pulmonary NTM infection
- To characterize macrophage and host immune responses in bronchiectasis
- To evaluate innovative diagnostics and treatment strategies
Impact
The UCSF INTEGRATE program supports nationally recognized research and multidisciplinary clinical care for patients with bronchiectasis and pulmonary NTM disease. Through collaborative clinical trials, translational science, and integrated care models, the program aims to improve diagnosis, expand therapeutic options, and enhance patient quality of life across Northern California and beyond.
Advancing Research. Improving Lives.
Support innovative NTM research that drives better outcomes for patients.
Shoshana Zha — shoshana.zha@ucsf.edu
Catherine DeVoe — catherine.devoe@ucsf.edu
Bella Cheng (Coordinator) — bella.cheng@ucsf.edu
Project Overview
The UCSF INTEGRATE program combines multidisciplinary expertise, translational science, and patient-centered care to accelerate advances in diagnosis, treatment, and research for pulmonary NTM disease and bronchiectasis.